Bioactivity | DF 461 is a sterol synthase inhibitor with significant inhibitory activity. DF 461 shows high selectivity for the liver and can effectively inhibit cholesterol synthesis in rat liver. DF 461 has shown the effect of lowering plasma lipids in repeated dosing studies in non-rodents[1]. |
CAS | 937051-40-6 |
Formula | C20H14Cl2F3N3O4 |
Molar Mass | 488.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Discovery of DF-461, a Potent Squalene Synthase Inhibitor |