Bioactivity | 2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase[1]. |
Invitro | 2',3'-cGMP sodium (10 nM-100 μM, 120 min) reduces the active transport of [3H]3’,5’-cGMP into inside-out vesicles from human erythrocytes[2].2',3'-cGMP sodium (2 μM) increases the ATPase activity[2]. |
Name | 2',3'-cGMP sodium |
CAS | 15718-49-7 |
Formula | C10H11N5NaO7P |
Molar Mass | 367.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sokurenko JV, et al. [Identification of 2',3'-cGMP as an intermediate of RNA catalytic cleavage by binase and evaluation of its biological action]. Bioorg Khim. 2015 Jan-Feb;41(1):37-43. Russian. [2]. Boadu E, et al. Inhibition by guanosine cyclic monophosphate (cGMP) analogues of uptake of [(3)H]3',5'-cGMP without stimulation of ATPase activity in human erythrocyte inside-out vesicles. Biochem Pharmacol. 2001 Aug 15;62(4):425-9. |