| Bioactivity | SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for SGF29-Tudor domain. SGF29-IN-1 exhibits activity against leukemia[1]. |
| Invitro | SGF29-IN-1 (20 μM) 抑制 SGF29 的 Tudor 结构域，阻断 SGF29 依赖性白血病细胞 MOLM13 和 MV4-11 中 H3K9 的乙酰化[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> SGF29-IN-1 相关抗体: Western Blot Analysis[1] Cell Line: |
| In Vivo | SGF29-IN-1 (5 mg/kg，腹腔注射，两天一次共 35 天) 可抑制白血病发展，且对 CD45 小鼠没有明显毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 6638-82-0 |
| Formula | C33H33N3O3 |
| Molar Mass | 519.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chan AKN, et al., Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery. Sci Adv. 2024 Feb 23;10(8):eadk3127. |