Bioactivity | (±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg[1]. |
Target | EC50: 0.3 mM (nAChR) |
In Vivo | (±)-Coniine hydrochloride (compound 1) (0.05 mg-0.2 mg; i.v.) 具有急性毒性,LD50 值为 7.7 mg/kg[1]。 Animal Model: |
Name | (±)-Coniine hydrochloride |
CAS | 15991-59-0 |
Formula | C8H18ClN |
Molar Mass | 163.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21(10):2061-4. |