PeptideDB

(S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2

CAS: F: C29H33N5O4 W: 515.60

(S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is the coupling conjugate of the E3 ubiquitin ligase ligand and linker f
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity (S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is the coupling conjugate of the E3 ubiquitin ligase ligand and linker for NX-2127 (HY-153220)[1].
Formula C29H33N5O4
Molar Mass 515.60
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Robbins D W, et al. Discovery and preclinical pharmacology of NX-2127, an orally bioavailable degrader of Bruton’s tyrosine kinase with immunomodulatory activity for the treatment of patients with B cell malignancies[J]. Journal of Medicinal Chemistry, 2024, 67(4): 2321-2336.