Bioactivity | (S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is the coupling conjugate of the E3 ubiquitin ligase ligand and linker for NX-2127 (HY-153220)[1]. |
Formula | C29H33N5O4 |
Molar Mass | 515.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Robbins D W, et al. Discovery and preclinical pharmacology of NX-2127, an orally bioavailable degrader of Bruton’s tyrosine kinase with immunomodulatory activity for the treatment of patients with B cell malignancies[J]. Journal of Medicinal Chemistry, 2024, 67(4): 2321-2336. |