| Bioactivity | NP3-253 is an NLRP3 inhibitor with oral activity and blood-brain barrier permeability, and NP3-253 can serve as a tool to further investigate the biological characteristics of NLRP3 in peripheral and neuroinflammatory model[1]. |
| CAS | 2557349-50-3 |
| Formula | C19H23F3N4O |
| Molar Mass | 380.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mackay A, et al. Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome[J]. Journal of Medicinal Chemistry, 2024. |
NP3-253
CAS: 2557349-50-3 F: C19H23F3N4O W: 380.41
NP3-253 is an NLRP3 inhibitor with oral activity and blood-brain barrier permeability, and NP3-253 can serve as a tool t
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