Bioactivity | (S)-GLPG0974 is the inactive isomer of GLPG0974 (HY-12940), and can be used as an experimental control. GLPG0974 is a free fatty acid receptor-2 (FFA2/GPR43) antagonist with an IC50 of 9 nM. | ||||||||||||
Name | (S)-GLPG0974 | ||||||||||||
CAS | 2326220-69-1 | ||||||||||||
Formula | C25H25ClN2O4S | ||||||||||||
Molar Mass | 485.00 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Pizzonero M, et al. Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic. J Med Chem. 2014 Dec 11;57(23):10044-57. |