PeptideDB

(S)-GLPG0974

CAS: 2326220-69-1 F: C25H25ClN2O4S W: 485.00

(S)-GLPG0974 is the inactive isomer of GLPG0974 (HY-12940), and can be used as an experimental control. GLPG0974 is a fr
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Bioactivity (S)-GLPG0974 is the inactive isomer of GLPG0974 (HY-12940), and can be used as an experimental control. GLPG0974 is a free fatty acid receptor-2 (FFA2/GPR43) antagonist with an IC50 of 9 nM.
Name (S)-GLPG0974
CAS 2326220-69-1
Formula C25H25ClN2O4S
Molar Mass 485.00
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Pizzonero M, et al. Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic. J Med Chem. 2014 Dec 11;57(23):10044-57.