| Bioactivity | (16R)-Epothilone D is the inactive isomer of Epothilone D (HY-15278), and can be used as an experimental control. Epothilone D (KOS 862) is a potent microtubule stabilizer. |
| Name | (16R)-Epothilone D |
| Formula | C27H41NO5S |
| Molar Mass | 491.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6. [2]. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302. |