Bioactivity | (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997)[1]. |
Invitro | (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) hydrochloride 是一种 κ 阿片受体 (κ opioid receptor) 激动剂,活性低于 (-) 反式对映体的 (-)-Trans-(1S,2S)-U-50488 (HY-15997)。 |
Name | (+)-U-50488 |
CAS | 67198-17-8 |
Formula | C19H26Cl2N2O |
Molar Mass | 369.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223(2):335-339. |