Oleoyl-D-lysine_product_DataBase

Bioactivity	Oleoyl-D-lysine is a selective Glycine Transporter-2 (GlyT2) inhibitor based on lipid. Oleoyl-D-lysine reverses neuropathic pain in mice, shows antidrowsiness effect on chronic neuropathic pain. Oleoyl-D-lysine is safe and effective without respiratory depression[1].
Target	Glycine Transporter-2 (GlyT2)
In Vivo	Oleoyl-D-lysine effectively reverses neuropathic pain in a mouse model of chronic neuropathic (chronic constriction injury) pain, reaching a peak analgesic dose of 30 mg/kg without causing respiratory depression; resultig mild side effects at 100 mg/kg without causing convulsions[1].
Name	Oleoyl-D-lysine
CAS	2240164-55-8
Formula	C24H46N2O3
Molar Mass	410.63
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Wilson BS, et al. Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice. J Pharmacol Exp Ther. 2022 Sep;382(3):246-255.

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