| Bioactivity | ω-conotoxin MoVIA is a potent and selective Cav2.2 inhibitor with an IC50 of 0.33 μM in SH-SY5Y fluorimetric hCav2.2 assay[1]. |
| Target | IC50: 0.33 μM (hCav2.2) |
| Name | ω-conotoxin MoVIA |
| Sequence | Cys-Lys-Pro-{Hyp}-Gly-Ser-Lys-Cys-Ser-{Hyp}-Ser-Met-Arg-Asp-Cys-Cys-Thr-Thr-Cys-Ile-Ser-Tyr-Thr-Lys-Arg-Cys-Arg-Lys-Tyr-Tyr-Asn (Disulfide bridge: Cys1-Cys16,Cys8-Cys19,Cys15-Cys26) |
| Shortening | CKP-{Hyp}-GSKCS-{Hyp}-SMRDCCTTCISYTKRCRKYYN (Disulfide bridge: Cys1-Cys16,Cys8-Cys19,Cys15-Cys26) |
| Formula | C147H233N45O47S7 |
| Molar Mass | 3607.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sousa SR, et al. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Sci Rep. 2018 Sep 7;8(1):13397. |
ω-conotoxin MoVIA
CAS: F: C147H233N45O47S7 W: 3607.15
ω-conotoxin MoVIA is a potent and selective Cav2.2 inhibitor with an IC50 of 0.33 μM in SH-SY5Y fluorimetric hCav2.2 a
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