PeptideDB

ω-Conotoxin CVID

CAS: 247207-64-3 F: C107H179N35O36S7 W: 2756.23

ω-Conotoxin CVID (Leconotide, AM336, CNSB004) blocks neuronal voltage sensitive calcium channel.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity ω-Conotoxin CVID (Leconotide, AM336, CNSB004) blocks neuronal voltage sensitive calcium channel[1].
Name ω-Conotoxin CVID
CAS 247207-64-3
Sequence Cys-Lys-Ser-Lys-Gly-Ala-Lys-Cys-Ser-Lys-Leu-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Ser-Gly-Thr-Val-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16,Cys8-Cys20,Cys15-Cys27)
Shortening CKSKGAKCSKLMYDCCSGSCSGTVGRC-NH2 (Disulfide bridge:Cys1-Cys16,Cys8-Cys20,Cys15-Cys27)
Formula C107H179N35O36S7
Molar Mass 2756.23
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Anton Kolosov, et al. CNSB004 (Leconotide) Causes Antihyperalgesia Without Side Effects When Given Intravenously: A Comparison with Ziconotide in a Rat Model of Diabetic Neuropathic Pain.Pain Med. 2010 Feb;11(2):262-73.