| Bioactivity | PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells.?PSMA-1 is selected and polyarginine sequences R6?or R9?were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1, to track PSMA binding on PCa cells[1].? |
| Target | IC50: PSMA |
| Name | PSMA targeting peptide |
| CAS | 2042750-71-8 |
| Sequence | Gly-Arg-Phe-Leu-Thr-Gly-Gly-Thr-Gly-Arg-Leu-Leu-Arg-Ile-Ser |
| Shortening | GRFLTGGTGRLLRIS |
| Formula | C70H122N24O19 |
| Molar Mass | 1603.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Christopher N Cultrara, et al. Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA. Mol Ther Nucleic Acid. 019 Dec 6:18:863-870. |
PSMA targeting peptide
CAS: 2042750-71-8 F: C70H122N24O19 W: 1603.87
PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated prot
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