| Bioactivity | δ-Tocotrienol prodrug-1 (compound 5b) is a prodrug of δ-tocotrienol (HY-122778). δ-Tocotrienol prodrug-1 shows radioprotective efficacy. δ-Tocotrienol prodrug-1 promotes the hematopoietic progenitor and stem cell regeneration in murine bone marrow and spleen[1]. |
| In Vivo | δ-Tocotrienol prodrug-1 (compound 5b) (100 mg/kg; s.c. once) 在小鼠中显示 30 天内存活率为 90%[1]。药代动力学参数[1]。 Parameters |
| CAS | 128254-90-0 |
| Formula | C31H44O5 |
| Molar Mass | 496.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zuo Z, et al. Radioprotective effectiveness of a novel delta-tocotrienol prodrug on mouse hematopoietic system against 60Co gamma-ray irradiation through inducing granulocyte-colony stimulating factor production. Eur J Med Chem. 2024 Apr 5;269:116346. |
δ-Tocotrienol prodrug-1
CAS: 128254-90-0 F: C31H44O5 W: 496.68
δ-Tocotrienol prodrug-1 (compound 5b) is a prodrug of δ-tocotrienol (HY-122778). δ-Tocotrienol prodrug-1 shows radiop
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