| Bioactivity | δ-Theraphotoxin-Hm1b is a 42-amino acid peptide isolated from Togo starburst tarantula (Heteroscodra maculata) venom. δ-Theraphotoxin-Hm1b selectively inhibits inactivation of NaV1.1 but have no effect on NaV1.7[1]. |
| Name | δ-Theraphotoxin-Hm1b |
| Sequence | Glu-Cys-Arg-Tyr-Leu-Phe-Gly-Gly-Cys-Lys-Thr-Thr-Ala-Asp-Cys-Cys-Lys-His-Leu-Gly-Cys-Arg-Thr-Asp-Leu-Tyr-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Phe (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28) |
| Shortening | ECRYLFGGCKTTADCCKHLGCRTDLYYCAWDGTF (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28) |
| Formula | C169H241N45O50S6 |
| Molar Mass | 3895.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alexander Mueller, et al. Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions. ACS Pharmacol Transl Sci. 2020 Feb 19;3(3):535-546. |
δ-Theraphotoxin-Hm1b
CAS: F: C169H241N45O50S6 W: 3895.38
δ-Theraphotoxin-Hm1b is a 42-amino acid peptide isolated from Togo starburst tarantula (Heteroscodra maculata) venom.
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