| Bioactivity | δ-Theraphotoxin-Hm1a toxin is a selective Nav1.1 activator. δ-Theraphotoxin-Hm1a toxin elicits pain and touch sensitivity. δ-Theraphotoxin-Hm1a toxin can be used for the research of irritable bowel syndrome[1]. |
| Target | Nav1.1 |
| Name | δ-Theraphotoxin-Hm1a toxin |
| Sequence | Glu-Cys-Arg-Tyr-Leu-Phe-Gly-Gly-Cys-Ser-Ser-Thr-Ser-Asp-Cys-Cys-Lys-His-Leu-Ser-Cys-Arg-Ser-Asp-Trp-Lys-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Phe-Ser-NH2 (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28) |
| Shortening | ECRYLFGGCSSTSDCCKHLSCRSDWKYCAWDGTFS-NH2 (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28) |
| Formula | C170H240N48O53S6 |
| Molar Mass | 3996.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Osteen JD, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. 2016 Jun 23;534(7608):494-9. |
δ-Theraphotoxin-Hm1a toxin
CAS: F: C170H240N48O53S6 W: 3996.40
δ-Theraphotoxin-Hm1a toxin is a selective Nav1.1 activator. δ-Theraphotoxin-Hm1a toxin elicits pain and touch sensitiv
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