| Bioactivity | γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively[1]. |
| Target | IC50: 0.014 μM (Aβ42, human), 0.017 μM (Aβ42, mouse) |
| Name | γ-Secretase modulator 4 |
| CAS | 1420200-82-3 |
| Formula | C23H19FN4O2 |
| Molar Mass | 402.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bischoff FP, et al. Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1737-1745. |