| Bioactivity | RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively[1]. |
| Target | EC50: 0.22 μM (hRORγ), 0.15 μM (RORγt, human IL-17 cells) |
| Name | RORγt Inverse agonist 3 |
| CAS | 2364429-77-4 |
| Formula | C29H31Cl2N5O4S |
| Molar Mass | 616.56 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Amaudrut J, et al. Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1799-1806. |
RORγt Inverse agonist 3
CAS: 2364429-77-4 F: C29H31Cl2N5O4S W: 616.56
RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.