| Bioactivity | β-Secretase Inhibitor III is an extremely selective BACE1 inhibitor (Ki = 0.13 nM). |
| Name | β-Secretase Inhibitor III |
| Formula | C20H20F2N4O3S |
| Molar Mass | 434.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ueno T, et al. Discovery of Extremely Selective Fused Pyridine-Derived β-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions. J Med Chem. 2021 Oct 14;64(19):14165-14174. |