| Bioactivity | β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer[1][2]. |
| Invitro | β-Cembrenediol (25、50、100、200 µg/mL) 以剂量依赖性方式抑制生菜幼苗茎长和根长[1]。β-Cembrenediol (0、0.2、0.5、1、5、10 µM) 以剂量依赖性方式减少迁移和菌落形成[2]。β-Cembrenediol (5、10、20 µM；48 小时) 以剂量依赖性方式降低 TDO2、IDO1 的蛋白质表达[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> β-Cembrenediol 相关抗体: Western Blot Analysis[2] Cell Line: |
| In Vivo | β-Cembrenediol (15 mg/kg; p.o.; daily for 8 weeks) 对前列腺癌小鼠表现出抗肿瘤活性[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 57605-81-9 |
| Formula | C20H34O2 |
| Molar Mass | 306.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ren X, et al. Isolation, Identification, and Autotoxicity Effect of Allelochemicals from Rhizosphere Soils of Flue-Cured Tobacco. J Agric Food Chem. 2015 Oct 21;63(41):8975-80. [2]. Mudhish EA, et al. The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase. Nutrients. 2022 Apr 4;14(7):1505. |