| Bioactivity | β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. |
| Invitro | β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer's disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. |
| Name | β-Amyloid (1-14),mouse,rat |
| Shortening | DAEFGHDSGFEVRH |
| Formula | C69H95N21O24 |
| Molar Mass | 1603.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen GF, et al. Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacol Sin. 2017 Sep;38(9):1205-1235. |