α-Conotoxin EI

CAS: 170663-33-9 F: C4H3DTIN2P2SY W: 2093.38

α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β

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Bioactivity	α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[1][2][3].
Invitro	α-Conotoxin EI (10 µM) blocks muscle and ganglionic receptors, but less potent for the central nevous system receptor[3].α-Conotoxin EI (10 µM) blocks the α1β1γδ receptors with a τon of 4.9 s, and blocks the α3β4 receptor with a τon of 11 s[3].
Name	α-Conotoxin EI
CAS	170663-33-9
Shortening	RD-{Hyp}-CCYHPTCNMSNPQIC (Disulfide bridge: Cys4-Cys10;Cys5-Cys18)
Formula	C4H3DTIN2P2SY
Molar Mass	2093.38
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]