Bioactivity | μ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA) is a voltage-gated sodium channel (VGSC) blocker. μ-Conotoxin BuIIIA is a toxic peptide that can be obtained from the venom of Cone snails. μ-Conotoxin BuIIIA can be used in the study of neurological diseases[1]. |
Name | µ-Conotoxin BuIIIA |
Sequence | Val-Thr-Asp-Arg-Cys-Cys-Lys-Gly-Lys-Arg-Glu-Cys-Gly-Arg-Trp-Cys-Arg-Asp-His-Ser-Arg-Cys-Cys-NH2 (Disulfide bridge:Cys5-Cys16, Cys6-Cys22, and Cys12-Cys23) |
Shortening | VTDRCCKGKRECGRWCRDHSRCC-NH2 (Disulfide bridge:Cys5-Cys16, Cys6-Cys22, and Cys12-Cys23) |
Formula | C106H172N44O31S6 |
Molar Mass | 2751.17 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Holford M, et al. Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus. Toxicon. 2009 Jan;53(1):90-8. |