Bioactivity | sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively[1]. |
Target | IC50: 26 nM (sPLA2 -X), 310nM (sPLA2-IIa), 2230 nM (sPLA2-V) |
Name | sPLA2-X Inhibitor 31 |
CAS | 2241025-50-1 |
Formula | C19H15F3N2O4 |
Molar Mass | 392.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Knerr L, et al. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X(sPLA2-X) Inhibitors. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599. |