| Bioactivity | sEH inhibitor-1 (compound TCPU ) is a potent and oral active inhibitor of sEH (soluble epoxide hydrolase) with IC50s of 0.4 and 5.3 nM in human and murine, respectively[1]. |
| Target | sEH |
| In Vivo | Pharmacokinetic parameters of sEH inhibitor-1 (TCPU) after oral gavage with a non-compartmental analysis[1]. Doses (mg/kg) |
| Name | sEH inhibitor-1 |
| CAS | 1208549-68-1 |
| Formula | C17H20F3N3O3 |
| Molar Mass | 371.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu JY, et al. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013;48(4-5):619-627. |
sEH inhibitor-1
CAS: 1208549-68-1 F: C17H20F3N3O3 W: 371.35
sEH inhibitor-1 (compound TCPU ) is a potent and oral active inhibitor of sEH (soluble epoxide hydrolase) with IC50s of
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