| Bioactivity | pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1]. |
| Target | IC50: 0.37 nM (Kras G12C), 0.19 nM (Kras G12V) |
| Name | pan-KRAS-IN-4 |
| CAS | 2885961-55-5 |
| Formula | C36H34F2N6O3 |
| Molar Mass | 636.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen Y, et al. Synthesis of Mutant KRAS modulators treating neoplastic, autoimmune diseases, and inflammatory disorders. World Intellectual Property Organization, WO2022271823 A1 2022-12-29. |
pan-KRAS-IN-4
CAS: 2885961-55-5 F: C36H34F2N6O3 W: 636.69
pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respect
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