| Bioactivity | p21PBP, a 20 amino-acid peptide, is an inhibitor of DNA replication. p21PBP specifically binds to purified proliferating cell nuclear antigen (PCNA) in tumour cell extracts. p21PBP is promising for research of cancers[1]. |
| Sequence | Gln-Asp-Lys-Thr-Arg-Tyr-Phe-His-Arg-Thr-Met-Ser-Arg-Ser-Lys-Ser-Ile-Arg-Leu-Phe |
| Shortening | QDKTRYFHRTMSRSKSIRLF |
| Formula | C112H181N37O30S |
| Molar Mass | 2557.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Warbrick E, et al. A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen. Curr Biol. 1995 Mar 1;5(3):275-82. |