| Bioactivity | nAChR antagonist 1 (compound B15) is an excellent α7 nAChR antagonist with an IC50 value of 3.3 μM. nAChR antagonist 1 can be used for researching schizophrenia, Alzheimer’s disease and inflammatory disorders[1]. |
| Target | IC50: 3.3 μM (α7 nAChR) |
| Name | nAChR antagonist 1 |
| Formula | C19H22N4O2 |
| Molar Mass | 338.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang H, et al. Design, synthesis and biological activities of piperidine-spirooxadiazole derivatives as α7 nicotinic receptor antagonists. Eur J Med Chem. 2020;207:112774. |