| Bioactivity | mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1]. |
| Name | mHTT-IN-1 |
| CAS | 2839311-21-4 |
| Formula | C18H19N7OS |
| Molar Mass | 381.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brom, et al. Preparation of thiazolopyrimidinone derivatives and uses thereof. World Intellectual Property Organization, WO2022194801 A1. 2022-09-22. |
mHTT-IN-1
CAS: 2839311-21-4 F: C18H19N7OS W: 381.45
mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.