| Bioactivity | mGAT3/4-IN-1 (compound 19b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.31 and 5.24, respectively. mGAT3/4-IN-1 exhibits a significant tactile allodynia reduction in diabetic neuropathic mice[1]. |
| Target | pIC50: 4.86 ± 0.10 (mGAT1), 4.98 ± 0.05 (mGAT2), 5.31 ± 0.04 (mGAT3), 5.24 ± 0.05 (mGAT4) |
| Name | mGAT3/4-IN-1 |
| CAS | 2556833-57-7 |
| Formula | C26H31ClN2O2S2 |
| Molar Mass | 503.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zaręba P, et al. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. Eur J Med Chem. 2020 Feb 15;188:111920. |
mGAT3/4-IN-1
CAS: 2556833-57-7 F: C26H31ClN2O2S2 W: 503.12
mGAT3/4-IN-1 (compound 19b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.31 and 5.24, respectively. mGAT3/4
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.