ARP is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and car
UKTT15 (compound 6) is an allosteric inhibitor of PARP1.
STING Degrader-1 (compound 2) is a potent STING degrader that covalently binds to STING and E3 ligase. STING Degrader-1
C14-SPM is a polyamine branched-chain lipidoid that can be used for the delivery of siRNA.
CoPoP is a kind of liposome vaccine adjuvant that can be used in cancer research.
BRD4 Inhibitor-33 (example 13) is a BRD4 inhibitor that can be used in acute kidney disease and chronic kidney disease r
AZ760 is a CCR8 antagonist. AZ760 shows excellent potency, good lipophilicity and high free fraction in blood. AZ760 exh
Ack1 inhibitor 2 (Example 259) is an Ack1 inhibitor (IC50: 0.46 μM).
DC-TEADin04 has weak inhibitory activity against TEAD4 palmitoylation.
BRD4 Inhibitor-32 (example 15) is a BRD4 inhibitor that can be used in acute kidney disease and chronic kidney disease r
C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with o
Transthyretin-IN-2 (Compound 36) is a transthyretin (TTR) amyloidsis inhibitor, with IC50 and pIC50 values of 1.31 μM a
TP receptor antagonist-1 (compound 7m) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 9.46
FGFR3-IN-9 (example27) is a selective FGFR3 inhibitor.
ALDH1A1-IN-5 (compound 25) is a potent aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with EC50 value of 83, 45, 43 µM
FGFR3-IN-8 (example91) is a selective FGFR3 inhibitor.
HDAC6-IN-37 (compound W5) is an inhibitor of HDAC6 and has neuroprotective effects. HDAC6-IN-37 can restore the morpholo
MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can b
B-Raf IN 17 (Compound 8e) is a potent and orally active type II multi-kinase inhibitor. B-Raf IN 17 exhibits potent cell
CSF1R-IN-21 (compound 7e) is a CSF-1R Inhibitor with an IC50 value of 31 nM. CSF1R-IN-21 inhibits CSF-1R auto-phosphoryl