| Bioactivity | Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid). It protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 μM.1 Ascorbyl tetraisopalmitate (20 μM) decreases IL-1α and prostaglandin E2 production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.2 Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents. |
| CAS | 183476-82-6 |
| Formula | C70H128O10 |
| Molar Mass | 1129.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ochiai, et al. A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. J. Dermatol. Sci. 44(1), 37-44 (2006). |
Ascorbyl tetra-2-hexyldecanoate
CAS: 183476-82-6 F: C70H128O10 W: 1129.76
Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid). It protects against UVB-, hydrogen
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