| Bioactivity | iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release[1]. |
| Name | iMAC2 hydrochloride |
| CAS | 335166-00-2 |
| Formula | C19H22Br2Cl2FN3 |
| Molar Mass | 542.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423(3):381-7. |
iMAC2 hydrochloride
CAS: 335166-00-2 F: C19H22Br2Cl2FN3 W: 542.11
iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD5
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