| Bioactivity | AANAT-IN-1 (compound 30) is a potent inhibitor (IC50: 10μM) of aralkylamine N-acetyltransferase (AANAT). AANAT is responsible for the synthesis of melatonin, which is involved in disorders such as seasonal affective disorder (SAD) in which melatonin levels are abnormally high[1]. |
| Target | 10μM (Aralkylamine N-acetyltransferase, AANAT) |
| Name | AANAT-IN-1 |
| Formula | C27H19FN2O4S2 |
| Molar Mass | 518.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hagemeister M, et al. Evaluation of Rhodanine Indolinones as AANAT Inhibitors. ChemMedChem. 2024 Jan 2;19(1):e202300567. |