| Bioactivity | human GALP (3-32) (Galanin-like peptide (3-32)) is a potent galanin receptor agonist with high affinity for both GalR1 (IC50=33 nM) and GalR2 (IC50=15 nM) in a competitive binding study. human GALP (3-32) exhibits the high potency in altering the extracellular acidification rate of SH-SY5Y cells transfected with GalR2 (EC50=360 nM)[1]. |
| Target | IC50: 15 nM (GalR2 in competitive binding study), 33 nM (GalR1 in competitive binding study) |
| Name | human GALP (3-32) |
| Sequence | Ala-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His-Leu-Pro-Gln-Met-Gly-Asp-Gln |
| Shortening | AHRGRGGWTLNSAGYLLGPVLHLPQMGDQ |
| Formula | C137H213N43O38S |
| Molar Mass | 3102.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lang R, et al. Pharmacological and functional characterization of galanin-like peptide fragments as potent galanin receptor agonists. Neuropeptides. 2005 Jun;39(3):179-84. |
human GALP (3-32)
CAS: F: C137H213N43O38S W: 3102.49
human GALP (3-32) (Galanin-like peptide (3-32)) is a potent galanin receptor agonist with high affinity for both GalR1 (
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