| Bioactivity | hsBCL9CT-24 is a Wnt/β-catenin (b-cat) pathway inhibitor with potent anti-tumor effect. hsBCL9CT-24 reactivates anti-cancer immune response suppressed by the oncogenic Wnt pathway and can be utilized for cancer research[1]. |
| CAS | 2094604-98-3 |
| Sequence | Ac-Leu-Gln-Thr-Leu-Arg-X-Ile-Gln-Arg-X-Leu-NH2 (X=(S)-2-(4'-pentenyl)-Ala) |
| Shortening | Ac-LQTLRXIQRXL-NH2 (X=(S)-2-(4'-pentenyl)-Ala) |
| Formula | C68H122N20O15 |
| Molar Mass | 1459.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng M, et al. Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells. Sci Adv. 2019 May 8;5(5):eaau5240. |
hsBCL9CT-24
CAS: 2094604-98-3 F: C68H122N20O15 W: 1459.82
hsBCL9CT-24 is a Wnt/β-catenin (b-cat) pathway inhibitor with potent anti-tumor effect. hsBCL9CT-24 reactivates anti-ca
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