hCYP3A4 Fluorogenic substrate 1

CAS: 186299-00-3 F: C19H12FNO2 W: 305.30

hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. hCYP3A4 Fluoroge

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Bioactivity	hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging[1].
Invitro	hCYP3A4 Fluorogenic substrate 1 (compound F8) (20 μM; 30 min) 在活 Hep3B2 细胞和 Huh-7 细胞的绿色通道处显示出明亮的荧光信号[1]。
In Vivo	hCYP3A4 Fluorogenic substrate 1 (10 mg/kg; i.v.) 可用于体内成像[1]。 Animal Model:
Name	hCYP3A4 Fluorogenic substrate 1
CAS	186299-00-3
Formula	C19H12FNO2
Molar Mass	305.30
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. He RJ, et al. Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug-Drug Interaction Studies. J Med Chem. 2023 May 25;66(10):6743-6755.

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