Bioactivity | hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1]. |
Invitro | hCAII-IN-8 (化合物 9; 100 μM; 24-48 小时) 与对照相比,对 HEK-293 T 细胞没有细胞毒性,细胞活力 >90%[1]。 |
Name | hCAII-IN-8 |
CAS | 952306-80-8 |
Formula | C15H16N2O5S |
Molar Mass | 336.36 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264. |