| Bioactivity | hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronidase with an IC50 of 773.9 μM[1]. |
| Invitro | The high-rank inhibitory potential of hCAII-IN-4 (Compound 12j) is attributed to the presence of the electron-donating OH group at C-7 of the coumarin motif[1]. |
| Name | hCAII-IN-4 |
| CAS | 2816080-18-7 |
| Formula | C31H23NO9 |
| Molar Mass | 553.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Arif N, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H, 5 H-pyrano [3, 2-c] chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. ACS Omega, 2022. |
hCAII-IN-4
CAS: 2816080-18-7 F: C31H23NO9 W: 553.52
hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronida
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