| Bioactivity | hCA IX-IN-2 is a potent and selectively hCA IX inhibitor with an KI value of 32.1 nM. hCA IX-IN-2 shows anti-proliferative activity[1]. |
| Invitro | hCA IX-IN-2 (compound 7c) (0-100 μM; 24 h) 显示抗增殖活性，对 HDF, MeWo, LN-229, SaOS-2, HepG2 细胞的 IC50 值分别为 62.5, 0.7121, 12.11, 7.834, 2.356 μM[1]。hCA IX-IN-2 (62.5 μM for NHDF, 2.365 μM for HepG2) 显着降低 NHDF 和 HepG2 细胞中 O2•- 的产生[1]。 Cell Cytotoxicity Assay[1] Cell Line: |
| Name | hCA IX-IN-2 |
| Formula | C23H24N2O4STe |
| Molar Mass | 552.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Petreni A, et al. Carbonic Anhydrase inhibitors bearing organotelluride moieties as novel agents for antitumor therapy. Eur J Med Chem. 2022 Dec 15;244:114811. |