Bioactivity | hAChE/hBuChE-IN-1 (compound C2) is a dual inhibitor of cholinesterase with IC50 values of 514 nM and 358 nM for hAChE and hBuChE respectively. hAChE/hBuChE-IN-1 has oral activity and improves cognition and spatial memory[1]. |
Formula | C30H31FN2O3 |
Molar Mass | 486.58 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mengzhen Li, et al. Design, synthesis and biological evaluation of galantamine analogues for cognitive improvement in Alzheimer's disease. Eur J Med Chem. 2025 Feb 15:284:117198. |