h-NTPDase8-IN-1

CAS: 716358-51-9 F: C10H10ClNO4S W: 275.71

h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h

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Bioactivity	h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1].
Target	IC50: 0.28 μM for h-NTPDase 8 (a human Nucleoside Triphosphate Diphosphohydrolase)
Name	h-NTPDase8-IN-1
CAS	716358-51-9
Formula	C10H10ClNO4S
Molar Mass	275.71
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.