| Bioactivity | eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC50s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis[1]. |
| Name | eIF4A3-IN-9 |
| CAS | 1402931-71-8 |
| Formula | C28H27NO8 |
| Molar Mass | 505.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78. |
eIF4A3-IN-9
CAS: 1402931-71-8 F: C28H27NO8 W: 505.52
eIF4A3-IN-9 (compound 57) is a silvestrol(HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation
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