| Bioactivity | CCβ is a simple 17-amino acid peptide designed in research. CCβ is able to mimic the conformational transition of proteins from α-helix to β-sheet, which is a key step in the aggregation of proteins associated with many diseases, such as Alzheimer's disease and prion disease. CCβ can be used to study diseases related to protein aggregation[1]. |
| CAS | 873582-78-6 |
| Sequence | Ser-Ile-Arg-Glu-Leu-Glu-Ala-Arg-Ile-Arg-Glu-Leu-Glu-Leu-Arg-Ile-Gly |
| Shortening | SIRELEARIRELELRIG |
| Formula | C88H157N29O27 |
| Molar Mass | 2053.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding F, et al. Direct observation of protein folding, aggregation, and a prion-like conformational conversion[J]. Journal of Biological Chemistry, 2005, 280(48): 40235-40240. |