| Bioactivity | ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2. | ||||||||||||
| Target | IC50: 49 nM (BD1), 32 nM (BD2) | ||||||||||||
| Name | ZL0454 | ||||||||||||
| CAS | 2229042-77-5 | ||||||||||||
| Formula | C18H22N4O3S | ||||||||||||
| Molar Mass | 374.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461. |
ZL0454
CAS: 2229042-77-5 F: C18H22N4O3S W: 374.46
ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1
Data collection：peptidedb@qq.com
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