PeptideDB

YS121

CAS: 916482-17-2 F: C20H26ClN3O2S W: 407.96

YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; I
Sales Email:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM). YS121 dose- dependently reduces PGE2 production with EC50=12 μM in IL-1β-stimulated A549 cells[1].
Name YS121
CAS 916482-17-2
Formula C20H26ClN3O2S
Molar Mass 407.96
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Hui-Hua Chang, et al. Identification and development of mPGES-1 inhibitors: where we are at?. Future Med Chem. 2011 Nov;3(15):1909-34.