| Bioactivity | YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner[1]. |
| CAS | 2417685-83-5 |
| Formula | C32H34F3N7O2 |
| Molar Mass | 605.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Arwood ML, et al. New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chem Biol. 2023 Jun 15;30(6):618-631.e12. |
YLIU-4-105-1
CAS: 2417685-83-5 F: C32H34F3N7O2 W: 605.65
YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting p
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