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(+)-LRH-1 modulator-1

CAS: F: C28H36N2O2S W: 464.66

(+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver r
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Bioactivity (+)-LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 has anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces the anti-inflammatory cytokine IL-10 and reduces the inflammatory cytokines IL-1b and TNFa[1].
Formula C28H36N2O2S
Molar Mass 464.66
Appearance 油状物
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Mays S G, et al. Development of the first low nanomolar liver receptor homolog-1 agonist through structure-guided design[J]. Journal of medicinal chemistry, 2019, 62(24): 11022-11034.