| Bioactivity | Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia[1]. |
| Target | IC50: 55 nM (xanthine oxidoreductase) |
| In Vivo | Xanthine oxidoreductase-IN-5 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 5 h 显示出降低急性高尿酸血症小鼠尿酸的作用[1]。 Animal Model: |
| Name | Xanthine oxidoreductase-IN-5 |
| CAS | 1026652-90-3 |
| Formula | C17H17N5O2 |
| Molar Mass | 323.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947. |
Xanthine oxidoreductase-IN-5
CAS: 1026652-90-3 F: C17H17N5O2 W: 323.35
Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthin
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This product is for research use only, not for human use. We do not sell to patients.