| Bioactivity | Xaliproden free base is an orally active and selective 5-HT1A receptor agonist. Xaliproden free base shows analgesic effect against acute tonic nociceptive pain and has neuroprotective effects. Xaliproden free base has an acute inhibitory effect on paclitaxel (HY-B0015)-induced mechanical allodynia by inhibiting the excessive response of primary afferent neurons[1]. |
| CAS | 135354-02-8 |
| Formula | C24H22F3N |
| Molar Mass | 381.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Andoh T, et al. Effects of xaliproden, a 5-HT₁A agonist, on mechanical allodynia caused by chemotherapeutic agents in mice. Eur J Pharmacol. 2013 Dec 5;721(1-3):231-6. |
Xaliproden free base
CAS: 135354-02-8 F: C24H22F3N W: 381.43
Xaliproden free base is an orally active and selective 5-HT1A receptor agonist. Xaliproden free base shows analgesic eff
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